Pregnancy Tests: Diagnostic pregnancy tests based on immunological reactions amongst HCG and anti-HCG might bring about Phony-adverse or Fake-favourable interpretations.
Hyperexcitability and abnormal movements happen to be claimed in patients pursuing just one administration of promethazine HCl. Thought ought to be supplied to your discontinuation of promethazine HCl also to the usage of other medications if these reactions arise.
Antihistamines and codeine are both of those contraindicated for use within the procedure of reduced respiratory tract indicators, like bronchial asthma.
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Usually do not acquire any benzodiazepines or medicines that can cause drowsiness or sleepiness all through cure with Promethazine Hydrochloride and Codeine Phosphate Oral Option. Talk to your Health care supplier for a listing of these medicines if You aren't certain.
The combination of promethazine hydrochloride and codeine phosphate really should be employed with caution in pediatric patient 6 decades and older (see WARNINGS – Use in Pediatric Patients).
No proof of tumorigenicity was observed in male and woman mice at codeine dietary doses as many as 400 mg/kg/working day (roughly similar to forty five instances the MRHD over a mg/m2 basis).
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In another research only one a hundred-mg/kg dose of codeine administered to Expecting mice reportedly resulted in delayed ossification inside the offspring.
Prevention and Charge of nausea and vomiting connected to certain varieties of anesthesia and medical procedures.
Usual Grownup dosage is 50 mg Promethazine HCl Oral Resolution with an properly lessened dose of narcotic or barbiturate as well as the demanded quantity of a belladonna alkaloid.
This may be worsened if taken with Liquor or other medication that also cause central nervous method (CNS) slowing such as sedatives, ache medicines, tranquilizers or sure prescription drugs for depression.
Mainly because opioid agonists might boost biliary tract pressure, with resultant increase in plasma amylase or lipase amounts, perseverance of such enzyme levels may be unreliable for 24 hrs following administration of the dose of Promethazine HCl and Codeine Phosphate Oral Option.
Warning really should be exercised when administering Promethazine HCl Oral Alternative to pediatric patients two many years of age and more mature due to the probable for fatal respiratory depression. Respiratory melancholy and apnea, at times affiliated with Demise, are strongly related to promethazine merchandise and they are circuitously associated with individualized body weight-centered dosing, which could normally allow Protected administration.